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PARP-Combination Therapy in the Community Setting: Practical Integration into Routine Care

by Stefan Ravello | May 11, 2026 | Oncology, PARP-Combination Therapy, Prostate Cancer

Prostate cancer is the most common solid cancer in men worldwide. Most men are diagnosed as having localized disease because of the widespread use of prostate-specific antigen screening. Men diagnosed as having clinically localized prostate cancer have multiple...

Adjuvant Therapy in HR+/HER2- Breast Cancer: Choosing and Managing CDK4/6 Inhibitors for Real-World Patients

by Stefan Ravello | May 11, 2026 | Breast Cancer, Oncology

Early-stage hormone receptor-positive, HER2-negative (HR+/HER2−) breast cancer is the most common breast cancer subtype, accounting for roughly two-thirds to three-quarters of all new breast cancer cases in the United States (U.S.). Endocrine therapy (ET) has long...

Beyond Clinical Trials: Addressing Real-World Evidence and Challenges in Multiple Myeloma Immunotherapy

by Stefan Ravello | May 11, 2026 | Hematology-Oncology, Multiple Myeloma

Multiple myeloma (MM) is a malignant plasma cell disorder and the second most common blood cancer in the United States (U.S.) Survival has improved markedly with modern therapies – the 5-year survival rate has more than doubled in recent decades – yet myeloma remains...

Implementing Blood‐Based Biomarker Testing for Earlier Diagnosis of Alzheimer’s Disease

by Stefan Ravello | Feb 11, 2026 | Neurology

The recent development and approval of blood-based biomarker tests (BBMs) for detecting neuropathologic changes associated with Alzheimer’s disease (AD) can enhance the care of patients by facilitating earlier diagnosis in both primary care and specialty settings....

Practical Strategies for Antidepressant Selection, Dosing and Augmentation in Major Depressive Disorder

by Stefan Ravello | Feb 11, 2026 | Psychiatry

In the United States (U.S.), major depressive disorder (MDD) is a prevalent and debilitating illness with a high burden of disease. Effective management of depression is therefore critical, yet achieving and sustaining remission remains challenging in practice. While...
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